Picking up goo chunks is very important to staying alive.
When Cell Division is ready, try to die in a position that makes it difficult for the enemy team to kill your bloblets.
Charging Elastic Slingshot from the fog of war will give opponents less time to react.
Zac heals from the goo that separates from him. You can crush the goo pieces by stepping on them.
Kill all of Zac's bloblets when he splits apart to stop him from reforming.
Silences, stuns, roots and knockups will all interrupt Zac when he is charging Elastic Slingshot.